references

Mushroom Extracts & Cancer

1 · Kuan, Y.-C., Wu, Y.-J., Hung, C.-L. & Sheu, F. Trametes versicolor Protein YZP Activates Regulatory B Lymphocytes – Gene Identification through De Novo Assembly and Function Analysis in a Murine Acute Colitis Model. PLoS ONE 8, e72422 (2013).

2 · Habtemariam, S. Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy. Biomedicines 8, 135 (2020).

3 · Wenner, C. A. et al. Polysaccharide-K augments docetaxel-induced tumor suppression and anti tumor immune response in an immunocompetent murine model of human prostate cancer. Int. J. Oncol. 40, 905–913 (2012).

4 · Lu, H. et al. Polysaccharide Krestin Is a Novel TLR2 Agonist that Mediates Inhibition of Tumor Growth via Stimulation of CD8 T Cells and NK Cells. Clin. Cancer Res. 17, 67–76 (2011).

5 · Jiang, J., Slivova, V., Valachovicova, T., Harvey, K. & Sliva, D. Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3. Int. J. Oncol. (2004) doi:10.3892/ijo.24.5.1093.

6 · Dudhgaonkar, S., Thyagarajan, A. & Sliva, D. Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum. Int. Immunopharmacol. 9, 1272–1280 (2009).

7 · Qu, L. et al. Anticancer effect of triterpenes from Ganoderma�lucidum�in human prostate cancer cells. Oncol. Lett. (2017) doi:10.3892/ol.2017.7153.

8 · Chen, L. et al. Prediction of anti-tumor chemical probes of a traditional Chinese medicine for mula by HPLC fingerprinting combined with molecular docking. Eur. J. Med. Chem. 83, 294–306 (2014).

9 · Gill, B. S., Kumar, S., & Navgeet. Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer. Mol. Biol. Rep. 43, 1411–1422 (2016).

10 · Liu, J. et al. Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms. Sci. Rep. 2, 905 (2012).

11 · M. Johnson, B. Ganoderic Acid DM: An Alternative Agent for the Treatment of Advanced Prostate Cancer. Open Prostate Cancer J. 3, 78–85 (2010).

12 · Yang, P.-P. et al. Effects of Hericium erinaceus Mycelium Extracts on the Functional Activity of Purinoceptors and Neuropathic Pain in Mice with L5 Spinal Nerve Ligation. Evid. Based Complement. Alternat. Med. 2020, 1–12 (2020).

13 · Qian, G., Pan, G.-F. & Guo, J.-Y. Anti-inflammatory and antinociceptive effects of cordymin, a peptide purified from the medicinal mushroom Cordyceps sinensis. Nat. Prod. Res. 26, 2358–2362 (2012).

14 · Leu, S.-F., Poon, S. L., Pao, H.-Y. & Huang, B.-M. The in Vivo and in Vitro Stimulatory Effects of Cordycepin on Mouse Leydig Cell Steroidogenesis. Biosci. Biotechnol. Biochem. 75, 723–731 (2011).

15 · Ashraf, S. et al. The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis. Sci. Rep. 9, 4696 (2019).

16 · Chen, X., Veena, R. K., Ramya, H., Janardhanan, K. K. & George, V. Gano oil: A novel antinociceptive agent extracted from Ganoderma lucidum inhibits paw oedema and relieves pain by hypnotic and analgesic actions of fatty acid amides. J. Ethnopharmacol. 263, 113144 (2020).

17 · Sakamoto, J. et al. Efficacy of adjuvant Immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trials. Cancer Immunol. Immunother. 55, 404–411 (2006).

18 · Ohwada, S. et al. Adjuvant immunochemotherapy with oral Tegafur/Uracil plus PSK in patients with stage II or III colorectal cancer: a randomised controlled study. Br. J. Cancer 90, 1003–1010 (2004).

19 · Kodama, N., Harada, N. & Nanba, H. A Polysaccharide, Extract From Grifola frondosa, Induces Th-1 Dominant Responses in Carcinoma-Bearing BALB/c Mice. Jpn. J. Pharmacol. 90, 357–360 (2002).

20 · Harada, N., Kodama, N. & Nanba, H. Relationship between dendritic cells and the D-fraction-induced Th-1 dominant response in BALB/c tumor-bearing mice. Cancer Lett. 192, 181–187 (2003).

21 · Ye, H. & Bennett Jenson, A. Ganoderma lucidum on the inhibition of colorectal cancer. Hematol. Med. Oncol. 2, (2017).

22 · Chen, N.-H., Liu, J.-W. & Zhong, J.-J. Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression. Pharmacol. Rep. 62, 150–163 (2010).

23 · Kim, S. P., Nam, S. H. & Friedman, M. Hericium erinaceus (Lion’s Mane) Mushroom Extracts In hibit Metastasis of Cancer Cells to the Lung in CT-26 Colon Cancer-Tansplanted Mice. J. Agric. Food Chem. 61, 4898–4904 (2013).

24 · Li, G. et al. Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers. J. Ethnopharmacol. 153, 521–530 (2014).

25 · Roldan‐Deamicis, A., Alonso, E., Brie, B., Braico, D. A. & Balogh, G. A. Maitake Pro4X has anti‐cancer activity and prevents oncogenesis in BALB c mice. Cancer Med. 5, 2427–2441 (2016).

26 · Nagashima, Y. et al. Lentinula edodes mycelia extract plus adjuvant chemotherapy for breast cancer patients: Results of a randomized study on host quality of life and immune function improvement. Mol. Clin. Oncol. 7, 359–366 (2017).

27 · Chen, S. et al. Anti-Aromatase Activity of Phytochemicals in White Button Mushrooms ( Agaricus bisporus ). Cancer Res. 66, 12026–12034 (2006).28 · Hetland, G., Johnson, E., Lyberg, T. & Kvalheim, G. The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation. Adv. Pharmacol. Sci. 2011, 1–10 (2011).

29 · Zhao, R. & He, Y. Network pharmacology analysis of the anti-cancer pharmacological mechanisms of Ganoderma lucidum extract with experimental support using Hepa1-6-bearing C57 BL/6 mice. J. Ethnopharmacol. 210, 287–295 (2018).

30 · Jiao, C. et al. Ganoderma lucidum spore oil induces apoptosis of breast cancer cells in vitro and in vivo by activating caspase-3 and caspase-9. J. Ethnopharmacol. 247, 112256 (2020).

31 · Tang, W., Liu, J.-W., Zhao, W.-M., Wei, D.-Z. & Zhong, J.-J. Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells. Life Sci. 80, 205–211 (2006).

32 · Li, C.-H. et al. Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. Life Sci. 77, 252–265 (2005).

33 · Fritz, H. et al. Polysaccharide K and Coriolus versicolor extracts for lung cancer: a systematic review. Integr. Cancer Ther. 14, 201–211 (2015).34 · Gill, B. S., Navgeet & Kumar, S. Ganoderma lucidum targeting lung cancer signaling: A review. Tumor Biol. 39, 101042831770743 (2017).

35 · Gao, J.-J. et al. New Triterpene Aldehydes, Lucialdehydes A-C, from Ganoderma lucidum and Their Cytotoxicity against Murine and Human Tumor Cells. Chem. Pharm. Bull. (Tokyo) 50, 837–840 (2002).

36 · Chen, N.-H., Liu, J.-W. & Zhong, J.-J. Ganoderic Acid Me Inhibits Tumor Invasion Through Down-Regulating Matrix Metalloproteinases 2/9 Gene Expression. J. Pharmacol. Sci. 108, 212–216 (2008).

37 · Cheng, S., Eliaz, I., Lin, J. & Sliva, D. Triterpenes from Poria cocos suppress growth and invasiveness of pancreatic cancer cells through the downregulation of MMP-7. Int. J. Oncol. 42, 1869–1874 (2013).

38 · Cheng, S. et al. Pachymic Acid Inhibits Growth and Induces Apoptosis of Pancreatic Cancer In Vitro and In Vivo by Targeting ER Stress. PLOS ONE 10, e0122270 (2015).

39 · Wang, C.-Z. et al. Effects of Ganoderma lucidum Extract on Chemotherapy-Induced Nausea and Vomiting in a Rat Model. Am. J. Chin. Med. 33, 807–815 (2005).

40 · Chen, L., Lin, Z. & Li, W. Ganoderma lucidum polysaccharides reduce methotrexate-induced small intestinal damage in mice via induction of epithelial cell proliferation and migration. Acta Pharmacol. Sin. 32, 1505–1512 (2011).

41 · Pillai, T. G., John, M. & Sara Thomas, G. Prevention of cisplatin induced nephrotoxicity by terpenes isolated from Ganoderma lucidum occurring in Southern Parts of India. Exp. Toxicol. Pathol. 63, 157–160 (2011).